PacBio (Pacific Biosciences) is a global genomics technology company that develops advanced DNA and RNA sequencing systems. The company’s solutions provide more accurate and comprehensive information about genomes, transcriptomes, and epigenetic changes, opening up new opportunities in biomedical, molecular biology, and genomics research.

HiFi Long-Read Sequencing

PacBio technology is based on HiFi long-read sequencing, which combines two essential advantages — long DNA reads and exceptionally high accuracy.

HiFi reads can reach lengths of up to 25 kb while providing an accuracy of 99.9%. This makes it possible to analyse complex, repetitive, and GC-rich regions of the genome that cannot always be fully explored using traditional short-read sequencing methods.

PacBio technology enables the identification of the following within a single study:

• single-nucleotide variants;
• small insertions and deletions;
• structural variants;
• tandem repeat expansions;
• haplotypes and allele phasing;
• DNA methylation and other epigenetic changes.

Sequencing native DNA without PCR amplification helps preserve important genetic and epigenetic information while reducing the risk of amplification-related errors and bias.

Wide Range of Applications

PacBio sequencing solutions are suitable for a broad range of research applications:

• whole-genome sequencing;
• targeted analysis of genes and genomic regions;
• research into rare and inherited diseases;
• cancer genomics;
• full-length RNA transcript and isoform analysis;
• microbial genomics and metagenomics;
• 16S rRNA sequencing;
• plant and animal genomics;
• gene therapy and drug development research;
• epigenetics research.

PacBio offers not only sequencing systems but also solutions for high-molecular-weight DNA extraction, library preparation, targeted sequencing, and data analysis. This makes it possible to create a well-designed and fully integrated workflow — from sample preparation to result interpretation.

PacBio Representative in Latvia

We are a PacBio representative in Latvia, helping laboratories, research institutions, and specialists select the most suitable sequencing systems, reagents, and workflows for their specific project objectives.

Contact us to receive a consultation, technical information, and a personalised offer for PacBio sequencing solutions.